Carbon Dioxide → 2-methyl-3-phenylthiophene

HRID 2216733Notes

Reaction equation

HRID 2216733 reaction equation
[CH3:1][C:2]1[S:6][C:5](C(O)=O)=[CH:4][C:3]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.C(=O)=O>>[CH3:1][C:2]1[S:6][CH:5]=[CH:4][C:3]=1[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 280Carbon DioxideHCID 8219265-methyl-4-phenyl-2-thiophenecarboxylic acid

Product 1

HCID 27753082-methyl-3-phenylthiophene

Procedure

The 5-methyl-4-phenyl-2-thiophenecarboxylic acid (54 g, 0.25 mol) prepared as described above was heated to 220–230° C. until the evolution of carbon dioxide ceased. The product was collected and distilled, b.p. 117° C./10 torr. Yield 30 g (70%).

Workup

  1. customThe product was collected
  2. distillationdistilled

Sources & evidence

ORD record
ord-f95385664c8840fbaff916d86df4fa43
Source dataset
uspto-grants-2006_09
Patent number
US07112638B2

Reaction notes

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