Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2216802Generated: October 31, 2026

HCID 21942442, compound → HCID 21942470, compound

https://huagongshe.com/reaction/2216802

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21942442HCID 21942442—
SolventFormic AcidHCID 284—
ProductHCID 21942470HCID 21942470—

Reaction Conditions

Temperature40 °C

Reaction Steps

A mixture of 3-(5-tert-butoxycarbonylpyrid-2-yl)-5-(3-cyano-5-fluorophenyl)-1,2,4-oxadiazole (69 mg, 0.19 mmol) in formic acid (98%, 3.5 mL) was heated at 40° C. for 17 hours. Evaporation of the solvent in vacuo afforded crude 3-(5-hydroxycarbonylpyrid-2-yl)-5-(3-cyano-5-flourophenyl)-1,2,4-oxadiazole as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07112595B2
Source datasetuspto-grants-2006_09
ORD IDord-c501d4c70485417fb9d914e4dada4eb3
Source noteuspto-grants-2006_09