HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lawesson's reagent → 3-Iodothiobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lawesson's reagent | HCID 87949 | — |
| Reactant | 3-Iodobenzamide | HCID 202425 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 3-Iodothiobenzamide | HCID 2759375 | 99% |
Reaction Steps
A mixture of 3-iodobenzamide (500 mg, 2.0 mmol) in toluene (5 mL) was treated with Lawesson's reagent (404 mg, 1 mmol) and the mixture heated at reflux for 1.6 hours. After cooling, silica gel chromatography afforded 260 mg (99% yield) of 3-iodothiobenzamide, as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07112595B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-ac53daa4d41f42e0ae4df53964d8081d |
| Source note | uspto-grants-2006_09 |