Phenol, 4-methoxy-2-nitro- → 2-Amino-4-methoxyphenol

Participants

Reaction Steps

Commercially available 4-methoxy-2-nitrophenol (1 g, 5.9 mmol) was dissolved in 10 mL methanol, and 10% Pd/C was added to the mixture. The mixture was hydrogenated in a Parr™ shaker at 30 psi until consumption of hydrogen ceased. The mixture was filtered through Celite and concentrated under reduced pressure, to yield 2-amino-4-methoxyphenol.

Provenance & Evidence