2-Methoxy-4-(3-oxoprop-1-en-1-yl)phenyl acetate → HCID 58843894, compound

HRID 2217642Notes

Reaction equation

[C:1]([O:4][C:5]1[CH:14]=[CH:13][C:8]([CH:9]=[CH:10][CH:11]=O)=[CH:7][C:6]=1[O:15][CH3:16])(=[O:3])[CH3:2]>C1C=CC=CC=1>[C:1]([O:4][C:5]1[CH:14]=[CH:13][C:8](/[CH:9]=[CH:10]/[CH:11]=[CH:2]/[C:1]([O:4][CH3:5])=[O:3])=[CH:7][C:6]=1[O:15][CH3:16])(=[O:3])[CH3:2]

Participants

Conditions

Temperature: 80 °C

Procedure

To a solution of 880 mg (4.0 mmol) of 4-acetoxy-3-methoxycinnamaldehyde in 100 mL of benzene, 2000 mg (6.0 mmol) of methyl (triphenylphosphoranilydene)acetate was added. The mixture was stirred at 80° C. for 4 h and passed through silica gel (eluent ethyl acetate-hexane, 1:1) to remove the excess of the Wittig reagent.

Workup

customto remove the excess of the Wittig reagent

Sources & evidence

ORD record: ord-255fd41691fd415f900ff2d37523064c
Source dataset: uspto-grants-2008_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07407989B2

Reaction notes

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