Toluene → 1-[4-(4-{1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl}phenoxymethyl)benzyl]-4-aza-1-azoniabicyclo[2.2.2]octane bromide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Toluene	HCID 1140	—
Edukt	Dabco	HCID 9237	—
Edukt	4-[4-(2-Bromomethyl benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-azetidin-2-one	HCID 21083183	—
Produkt	1-[4-(4-{1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl}phenoxymethyl)benzyl]-4-aza-1-azoniabicyclo[2.2.2]octane bromide	HCID 21083157	—

Reaktionsschritte

Compound (15) and DABCO were dissolved in toluene and reacted analogously to Example IV, giving the product (16) as a colorless solid of molecular weight 704.66 (C38H40BrF2N3O3); MS (ESI): 624.30 (MH+).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07407938B2
Quelldatensatz	uspto-grants-2008_08
ORD ID	ord-465c66f833394fb4ba5167ece0ba2e5b
Quellennotiz	uspto-grants-2008_08