HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N'-Dimethyl-1,3-propanediamine → HCID 11351999, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N'-Dimethyl-1,3-propanediamine | HCID 66978 | — |
| Reactant | N-(2,6-Dichloro-5-quinolinyl)-cyclohexaneacetamide | HCID 86012996 | — |
| Product | HCID 11351999 | HCID 11351999 | 79.4% |
Reaction Steps
Prepared according to the method of example 2, using N-(2,6-dichloro-5-quinolinyl)-cyclohexaneacetamide (Example 1 (a)) (100 mg) and N,N′-dimethyl-1,3-propanediamine (300 mg). Further purification by HPLC (Symmetry—0.1% aqueous trifluoroacetic acid/acetonitrile) followed by conversion to its hydrochloride salt as described in example 2, afforded the title compound as a solid (56 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07408065B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-020f860ced6142beb365f854ad46967c |
| Source note | uspto-grants-2008_08 |