HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-3-Pyrrolidinol → N-[6-Chloro-2-[(3R)-3-hydroxy-1-pyrrolidinyl]-5-quinolinyl]-cyclohexaneacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-3-Pyrrolidinol | HCID 2759337 | — |
| Reactant | N-(2,6-Dichloro-5-quinolinyl)-cyclohexaneacetamide | HCID 86012996 | — |
| Product | N-[6-Chloro-2-[(3R)-3-hydroxy-1-pyrrolidinyl]-5-quinolinyl]-cyclohexaneacetamide | HCID 11452035 | 17.4% |
Reaction Steps
Prepared according to the method of example 27, using N-(2,6-dichloro-5-quinolinyl)-cyclohexaneacetamide (Example 1(a)) (0.05 g) and (3R)-3-pyrrolidinol (0.052 g) to afford the title compound (0.01 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07408065B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-ec1559f53783494ebf2cdc097c8abccd |
| Source note | uspto-grants-2008_08 |