Ethyl piperazine-1-acetate → HCID 86609743, compound

HRID 2217874Notes

Reaction equation

HRID 2217874 reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:8]([C:12]([NH:14][CH2:15][CH:16]3[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]3)=[O:13])=[C:7]([Cl:22])[CH:6]=[CH:5][C:4]=2[N:3]=1.[N:23]1([CH2:29][C:30]([O:32][CH2:33][CH3:34])=[O:31])[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1>>[Cl:22][C:7]1[C:8]([C:12]([NH:14][CH2:15][CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)=[O:13])=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([N:26]1[CH2:25][CH2:24][N:23]([CH2:29][C:30]([O:32][CH2:33][CH3:34])=[O:31])[CH2:28][CH2:27]1)[CH:11]=[CH:10]2

Participants

3

Reactant 2

HCID 207112Ethyl piperazine-1-acetateHCID 860130222,6-dichloro-N-(cyclohexylmethyl)-5-quinolinecarboxamide

Product 1

HCID 86609743HCID 86609743, compound

Procedure

Prepared according to the method of example 30, using 2,6-dichloro-N-(cyclohexylmethyl)-5-quinolinecarboxamide Example 43(a)) (200 mg) and 1-piperazineacetic acid, ethyl ester (500 mg) to afford the subtitle compound as a solid (200 mg).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-238e09a4b9484c3dbf8bbf8ea5296333
Source dataset
uspto-grants-2008_08
Patent number
US07408065B2

Reaction notes

Loading…