HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-dichloro-N-(cyclohexylmethyl)-5-quinolinecarboxamide → HCID 68808929, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-dichloro-N-(cyclohexylmethyl)-5-quinolinecarboxamide | HCID 86013022 | — |
| Solvent | HCID 178510996 | HCID 178510996 | — |
| Product | HCID 68808929 | HCID 68808929 | 210.8% |
Reaction Steps
Prepared according to the method of example 67 (a) using 2,6-dichloro-N-(cyclohexylmethyl)-5-quinolinecarboxamide (prepared as in Example 43 (a)) (500 mg) and bromo(4-cyanobutyl)-zinc (30 mL, 0.5 M solution in tetrahydrofuran). Purification (SiO2, methanol:dichloromethane 1:200 as eluant) gave the sub-title compound as a solid (600 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07408065B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-e86c2198f58a447798f70567bc02b6c3 |
| Source note | uspto-grants-2008_08 |