Trifluoroacetic acid → HCID 55299029, compound

Participants

Reaction Steps

To a stirred solution of (3S)-3-(2-cyanoethoxy)-1-pyrrolidinecarboxylic acid, 1,1-dimethylethyl ester (Example 107(a)) (1 g) in dichloromethane (10 mL) was added trifluoroacetic acid (3 mL). The mixture was stirred at room temperature for 30 minutes and then concentrated. Purification (Varian SCX cartridge, using methanol and then 10% ammonia in methanol as eluant) gave the sub-title compound (350 mg).

Provenance & Evidence