4-Piperidinecarbonitrile hydrochloride → HCID 68808815, 화합물

HRID 2217915노트

반응식

HRID 2217915 반응식
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:8]([C:12]([NH:14][CH2:15][CH:16]3[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]3)=[O:13])=[C:7]([Cl:22])[CH:6]=[CH:5][C:4]=2[N:3]=1.Cl.[C:24]([CH:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1)#[N:25]>>[Cl:22][C:7]1[CH:6]=[CH:5][C:4]2[N:3]=[C:2]([N:29]3[CH2:30][CH2:31][CH:26]([C:24]#[N:25])[CH2:27][CH2:28]3)[CH:11]=[CH:10][C:9]=2[C:8]=1[C:12]([NH:14][CH2:15][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1)=[O:13]

참가 물질

3

반응물 2

HCID 227446374-Piperidinecarbonitrile hydrochlorideHCID 860130222,6-dichloro-N-(cyclohexylmethyl)-5-quinolinecarboxamide

생성물 1

HCID 68808815HCID 68808815, 화합물

실험 절차

Prepared according to the method of example 51, using 2,6-dichloro-N-(cyclohexylmethyl)-5-quinolinecarboxamide Example 43(a)) (0.25 g), and 4-cyanopiperidine hydrochloride (0.25 g) to afford the title compound (0.27 g).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-edd62a653b534581960380a0f2b2a52f
출처 데이터셋
uspto-grants-2008_08
특허 번호
US07408065B2

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