5-Bromothiophene-2-sulfonyl chloride → 5-Bromo-N-(5-chloro-3-methoxy-2-pyrazinyl)-2-thiophenesulphonamide
Reaction equation
[Cl:1][C:2]1[N:3]=[C:4]([O:9][CH3:10])[C:5]([NH2:8])=[N:6][CH:7]=1.[Br:11][C:12]1[S:16][C:15]([S:17](Cl)(=[O:19])=[O:18])=[CH:14][CH:13]=1>>[Br:11][C:12]1[S:16][C:15]([S:17]([NH:8][C:5]2[C:4]([O:9][CH3:10])=[N:3][C:2]([Cl:1])=[CH:7][N:6]=2)(=[O:19])=[O:18])=[CH:14][CH:13]=1Participants
3
Procedure
Prepared by the method of Example 1 from 5-chloro-3-methoxy-2-pyrazinamine and 5-bromothiophenesulphonyl chloride.
Sources & evidence
- ORD record
- ord-92ec79ee3dd24f0392f93cf06fbcaf3e
- Source dataset
- uspto-grants-2008_08
- Patent number
- US07410972B2
Reaction notes
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