HCID 69017762, compound → HCID 86609053, compound

HRID 2217996Notes

Reaction equation

HRID 2217996 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([CH:12]=[CH:13][C:14]1[O:15][C:16]([N+:19]([O-:21])=[O:20])=[CH:17][CH:18]=1)[N:6]=[C:5]2[NH:22][C:23]1[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=1.[F:30]C1C=C2C(=CC=1F)N=C(C)NC2=O>>[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[F:30])[N:8]=[C:7]([CH:12]=[CH:13][C:14]1[O:15][C:16]([N+:19]([O-:21])=[O:20])=[CH:17][CH:18]=1)[N:6]=[C:5]2[NH:22][C:23]1[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 69017762HCID 69017762, compoundHCID 1357422826,7-Difluoro-2-methylquinazolin-4(1H)-one

Product 1

HCID 86609053HCID 86609053, compound

Procedure

This compound was prepared in the same manner as that described in Example I or the synthesis of 6-fluoro-2-[2-(5-nitro-2-furyl)vinyl]-4-(p-hydroxyanilino)quinazoline, by using 6,7-difluoro-2-methyl-4-(3H)quinazolinone (1 g) as a starting material.

Workup

  1. customThis compound was prepared in the same manner as

Sources & evidence

ORD record
ord-a2129d74f62649f296ca391c083ab891
Source dataset
uspto-grants-2008_08
Patent number
US07410974B2

Reaction notes

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