HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylboronic Acid → HCID 11441421, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylboronic Acid | HCID 66827 | — |
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Reactant | 3-(7-bromo-8-methoxy-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl)-benzonitrile | HCID 69287738 | — |
| Product | HCID 11441421 | HCID 11441421 | 30% |
Reaction Steps
Prepared from 3-(7-bromo-8-methoxy-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl)-benzonitrile Intermediate 9 using the same method described for Example 1 and instead of using benzene boronic acid, we used p-chlorophenyl boronic acid. The title compound (48 mg) was obtained as a white solid, (yield=30%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07410963B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-f4d03220055747b4a6c98da2a36476da |
| Source note | uspto-grants-2008_08 |