HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylboronic Acid → HCID 11223486, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylboronic Acid | HCID 66827 | — |
| Reactant | 4-Cyanophenylboronic acid | HCID 2734326 | — |
| Reactant | 3-(7-bromo-8-methoxy-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl)-benzonitrile | HCID 69287738 | — |
| Product | HCID 11223486 | HCID 11223486 | 14% |
Reaction Steps
Prepared from 3-(7-bromo-8-methoxy-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl)-benzonitrile Intermediate 9 using the same method described for Example 1 and instead of using benzene boronic acid, we used 4-cyanophenyl boronic acid. The title compound (25 mg) was obtained as a beige solid, (yield=14%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07410963B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-af0cba88841541f5afc6d915d9d8a610 |
| Source note | uspto-grants-2008_08 |