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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2218086Generated: October 26, 2026

1-(Benzyl-methyl-amino)-heptan-3-ol → (4-Cyclohexyl-3-hydroxy-butyl)-methyl-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/2218086

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Benzyl-methyl-amino)-heptan-3-olHCID 17981933—
Reactant(4-Cyclohexyl-3-oxo-butyl)-methyl-carbamic acid tert-butyl esterHCID 59769551—
Product(4-Cyclohexyl-3-hydroxy-butyl)-methyl-carbamic acid tert-butyl esterHCID 59769577—

Reaction Steps

Using a method similar to that for 1-(Benzyl-methyl-amino)-heptan-3-ol, (4-cyclohexyl-3-oxo-butyl)-methyl-carbamic acid tert-butyl ester affords the title compound: 1H NMR (CDCl3) δ 3.90-3.80 (m, 1H), 3.62-3.52 (m, 1H), 2.88-2.96 (m, 1H), 2.83 (3H), 1.80-1.60 (m, 6H), 1.56-1.32 (m, 3H), 1.47 (s, 9H), 1.31-1.08 (m, 4H), 0.98-0.77 (m, 2H),

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07410982B2
Source datasetuspto-grants-2008_08
ORD IDord-3f014be0b0a34d108d2c4008ec459f51
Source noteuspto-grants-2008_08