Boron tribromide → HCID 59651990, compound

HRID 221824Notes

Reaction equation

HRID 221824 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([CH3:15])=[N:13][N:12]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)[C:11](=[O:22])[CH:10]=2)=[CH:5][CH:4]=1.B(Br)(Br)Br>C(Cl)Cl>[OH:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([CH3:15])=[N:13][N:12]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)[C:11](=[O:22])[CH:10]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 59652040HCID 59652040, compound

Product 1

HCID 59651990HCID 59651990, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

5-(4-Hydroxy-phenyl)-6-methyl-2-pyridin-2-yl-2H-pyridazin-3-one was prepared from 5-(4-Methoxy-phenyl)-6-methyl-2-pyridin-2-yl-2H-pyridazin-3-one and BBr3 in CH2Cl2 using the procedure described in Example 91 Step 3; Mp 252-4° C.; MS m/z 280 (M+H).

Sources & evidence

ORD record
ord-ae9e59774f674bb7a169b74bee456a59
Source dataset
uspto-grants-2012_06
Patent number
US08207168B2

Reaction notes

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