Phthalic Anhydride → HCID 178514963, compound

HRID 2218327Notes

Reaction equation

HRID 2218327 reaction equation
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[C:7]1(=O)[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9](=[O:16])[O:8]1>O1CCOCC1>[N:4]1[N:3]=[C:2]([N:1]2[C:7](=[O:8])[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[C:9]2=[O:16])[NH:6][CH:5]=1

Participants

4

Reactant 2

HCID 6811Phthalic AnhydrideHCID 178418311HCID 178418311, compound

Product 1

HCID 178514963HCID 178514963, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Conditions

Temperature
120 °C

Procedure

3-Amino-[1,2,4]triazole (8.40 g, 100 mmol) and isobenzofuran-1,3-dione (14.8 g, 100 mmol) were suspended in 1,4-dioxane (200 ml) and heated at 120° C. for 2 days. After the reaction mixture was cooled down at room temperature, the resulting precipitate was filtered, and the cake was washed with H2O then EtOAc to obtain the intended compound as a colorless solid.

Workup

  1. temperatureAfter the reaction mixture was cooled down at room temperature
  2. filtrationthe resulting precipitate was filtered
  3. washthe cake was washed with H2O

Sources & evidence

ORD record
ord-fa1229c6be9b4f5ca86d901d5f860edc
Source dataset
uspto-grants-2008_08
Patent number
US07410976B2

Reaction notes

Loading…