Aniline → HCID 10253193, compound

HRID 2218392Notes

Reaction equation

HRID 2218392 reaction equation
[Cl:1][C:2]1[C:3](Cl)=[C:4]2[N:10]=[C:9]([C:11]3[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH2:19][N:20]4[CH2:25][CH2:24][O:23][CH2:22][CH2:21]4)=[CH:13][CH:12]=3)[NH:8][C:5]2=[N:6][CH:7]=1.[NH2:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[Cl:1][C:2]1[C:3]([NH:27][C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)=[C:4]2[NH:10][C:9]([C:11]3[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH2:19][N:20]4[CH2:21][CH2:22][O:23][CH2:24][CH2:25]4)=[CH:13][CH:12]=3)=[N:8][C:5]2=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 6115AnilineHCID 178478272HCID 178478272, compound

Product 1

HCID 10253193HCID 10253193, compoundYield 44%

Procedure

By a procedure similar to that of Example 219 but using 6,7-dichloro-2-[4-(2-morpholin-4-ylethoxy)phenyl]-3H-imidazo[4,5-b]pyridine (Example 206) and aniline, the title compound was obtained in 44% yield.

Sources & evidence

ORD record
ord-6240b04937634982b2287df163d0d114
Source dataset
uspto-grants-2008_08
Patent number
US07410966B2

Reaction notes

Loading…