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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2218405Generated: October 31, 2026

Aniline → HCID 178495921, compound

https://huagongshe.com/reaction/2218405

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
ReactantHCID 178510329HCID 178510329—
ProductHCID 178495921HCID 1784959212%

Reaction Conditions

Temperature180 °C

Reaction Steps

7-Chloro-2-[4-(2-morpholin-4-ylethoxy)phenyl]-3H-imidazo[4,5-b]pyridine-6-carbonitrile (Example 243) (0.050 g, 0.13 mmol) was dissolved in aniline (2 ml) and heated at 180° C. for 3 h in a sealed vial. The excess aniline was evaporated and the crude product was purified by HPLC-C18, giving the title product (0.001 g, 2%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07410966B2
Source datasetuspto-grants-2008_08
ORD IDord-cc3fc83042644f33b21a217fd63053d0
Source noteuspto-grants-2008_08