Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | HCID 178510329 | HCID 178510329 | — |
| Product | HCID 178495921 | HCID 178495921 | 2% |
Reaction Steps
7-Chloro-2-[4-(2-morpholin-4-ylethoxy)phenyl]-3H-imidazo[4,5-b]pyridine-6-carbonitrile (Example 243) (0.050 g, 0.13 mmol) was dissolved in aniline (2 ml) and heated at 180° C. for 3 h in a sealed vial. The excess aniline was evaporated and the crude product was purified by HPLC-C18, giving the title product (0.001 g, 2%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07410966B2 |
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| Source dataset | uspto-grants-2008_08 |
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| ORD ID | ord-cc3fc83042644f33b21a217fd63053d0 |
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| Source note | uspto-grants-2008_08 |
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