5-Chloro-4-methyl-3-nitropyridin-2-amine → 5-Chloro-4-methylpyridine-2,3-diamine

HRID 2218410Notes

Reaction equation

HRID 2218410 reaction equation
[NH2:1][C:2]1[C:7]([N+:8]([O-])=O)=[C:6]([CH3:11])[C:5]([Cl:12])=[CH:4][N:3]=1>[Ni]>[Cl:12][C:5]1[C:6]([CH3:11])=[C:7]([NH2:8])[C:2]([NH2:1])=[N:3][CH:4]=1

Participants

3

Reactant 1

HCID 214641365-Chloro-4-methyl-3-nitropyridin-2-amine

Product 1

HCID 445580925-Chloro-4-methylpyridine-2,3-diamine

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

The title compound was prepared by reduction of 2-amino-5-chloro-4-methyl-3-nitropyridine (prepared according to the route described in Example 206) using Raney Nickel as described above.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-bd3ba396be05428889314d5cbe100f5e
Source dataset
uspto-grants-2008_08
Patent number
US07410966B2

Reaction notes

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