Thionyl Chloride → HCID 178492968, compound

Participants

Reaction Steps

2-[4-(6-Chloro-7-methoxy-3H-imidazo[4,5-b]pyridin-2-yl)phenoxy]ethanol (0.26 g, 0.8 mmol) was dissolved in SOCl2 (10 ml). The reaction mixture was refluxed for 3 h, after which the excess SOCl2 was removed by evaporation. Repetitive co-evaporation with toluene yielded pure title compound (0.275 g, 100%).

Provenance & Evidence