HCID 11339937, compound → HCID 67048053, compound

Participants

Reaction Steps

By following the procedure described for the preparation of 6a from 5a, 5b (100 mg, 0.21 mmol) gave 6b as a white foam (78 mg, 88%). [α]D−44 (c 1.0, CHCl3); IR λ 3004, 2954, 2360, 2213, 1747, 1644, 1481, 1213, 1164, 792; 1H NMR (400 MHz, CDCl3) 8.12 (d, J=8.2 Hz, 1H), 7.89 (d, J=7.9 Hz, 1H), 7.75 (d, J=8.7 Hz, 1H), 7.62-7.51 (m, 2H), 7.34 (t, 1H), 6,89 (d, J=7.1 Hz, 1H) 5.74 (dd, J=6.7, 2.2 Hz, J=9.8, 2.2 Hz, 1H), 1.27-1.21 (m, 1H), 0.69-0.65 (m, 2H); 0.55-0.53 (m, 2H): 13C NMR (100 MHz, CDCl3) (167.7, 162.9, 158.6, 155.6, 133.8, 132.4, 131.7, 128.9, 127.6, 126.4, 125.9, 125.5, 124.1, 122.8, 115.2, 114.5, 101.7, 63.5, 53.6, 34.8, 31.7, 11.3, 7.7, 7.2; HRMS (FAB+) calcd for C24H21N2O3S 417.1267, obsd 417.1289.

Provenance & Evidence