HCID 11164883, compound → HCID 11209581, compound

Participants

Reaction Steps

By following the procedure described for the preparation of 6a from 5a, 5c (150 mg, 0.39 mmol) gave 6c as a pale yellow foam (110 mg, 86%): [α]D−161 (c 1.0, CHCl3); IR λ 3012, 2956, 2215, 1749, 1648, 1440, 1365, 1257, 1216 cm−1. 1H NMR (400 MHz, CDCl3) δ 7.50-7.39 (m, 3H), 7.25-7˜(m, 2H), 5.72 (dd, J=8.8, 2.3, 1H), 3.85 (s, 3H), 3.72 (dd, J=11.9, 8.8, 1H), 3.51 (dd, J=11.9, 2.3, 1H), 2.21 (s, 3H); 13C NMR (100 MHz, CDCl3) δ 167.6, 158.8, 158.4, 154.3, 135.0, 129.7, 129.5, 129.1 (splitted), 128.9, 116.5, 115.4, 99.5, 64.1, 53.5, 31.7, 20.0; HRMS (FAB+) calcd for C17H15N2O3S 327.0803, obsd 327.0805.

Provenance & Evidence