3-Methyl-2-butanone → HCID 86600552, compound

Participants

Reaction Steps

To a three-necked flask equipped with mechanical stirrer and a reflux condenser were added 50 ml of acetic acid, 15 ml (140 mmol) of 3-methyl-2-butanone, 16.2 g (60 mmol) of 2-hydrazino-1,4-benzenedisulfonic acid and 13 g (133 mmol) of potassium acetate. The mixture was heated to reflux for 8 h and then cooled to room temperature. The brownish precipitate was filtered off and washed with acetic acid and acetonitrile. Yield: 13.8 g (58%) of the raw product (1k). 1H-NMR (200 MHz, DMSO-d6), δ, ppm: 7.67 (1H, arom., d, 8.1 Hz), 7.59 (1H, arom., d, 8.2 Hz), 2.44 (3H, CH3, s), 1.57 (6H, (CH3)2, s).

Provenance & Evidence