3-(Trifluoromethyl)phenylboronic acid → HCID 59770205, compound

Participants

Reaction Steps

Combine 5-bromomethylene-10,11-dihydro-5H-dibenzo[a,d]cycloheptene (0.5 g, 1.75 mmol) and 3-(trifluoromethyl)phenyl boronic acid (0.33 g, 1.75 mmol) using procedures essentially as described in Example 219, below. Pass through a plug of silica gel equilibrated with hexanes. Concentrate the filtrate to give the title product. Analysis for C23H17F3: Calcd: C, 78.84 H. 4.89; Found: C, 79.03.H, 5.03. HPLC (ISO80-10M)) t=16.30 min (98%).

Provenance & Evidence