HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Fluoro-5-methoxyphenyl)boronic acid → HCID 59770563, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Fluoro-5-methoxyphenyl)boronic acid | HCID 2763243 | — |
| Reactant | 5-bromomethylene-10,11-dihydro-5H-dibenzo[a,d]cycloheptene | HCID 5257940 | — |
| Product | HCID 59770563 | HCID 59770563 | 52% |
Reaction Steps
Following procedures essentially as described in Example 219, below, and using 3-fluoro-5-methoxyphenylboronic acid (300 mg, 1.76 mmol) and 5-bromomethylene-10,11-dihydro-5H-dibenzo[a,d]cycloheptene (450 mg, 1.6 mmol)provides 275 mg of title compound in 52% yield as a pale yellow oil. HPLC shows 97% purity.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07411072B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-f0efb8497c67490aa737347b8ed08ec8 |
| Source note | uspto-grants-2008_08 |