HCID 68937235, compound → HCID 59769937, compound

Participants

Reaction Steps

Dissolve 3-(1-fluoro-10,11-dihydro-dibenzo[a,d]cyclohepten-5-ylidenemethyl)-phenol (170 mg, 0.54 mmol) in EtOH (5 mL) and add 10% Pd/C (50 mg). Stir for 18 h under an atmosphere of hydrogen. Filter and concentrate. Purify the crude product using column chromatography (10% EtOAc/hexane→25% EtOAc/hexane) to give 98 mg (57%) product as a colorless oil. MS (ES) 317 (M−1). HPLC shows 99% purity.

Provenance & Evidence