HCID 68935775, compound → HCID 59769936, compound

Participants

Reaction Steps

Dissolve 150 mg (0.38 mmol) N-[3-(1-fluoro-10,11-dihydro-dibenzo[a,d]cyclohepten-5-ylidenemethyl)-phenyl]-methanesulfonamide in EtOH (5 mL) and add 10% Pd/C (50 mg). Stir for 18 h under an atmosphere of hydrogen. Filter and concentrate. Purify the crude product using column chromatography (10% EtOAc/hexane→25% EtOAc/hexane) to give 6 mg product as a colorless oil. MS (ES) 394 (M−1). HPLC shows 99% purity.

Provenance & Evidence