HCID 68936986, compound → HCID 59770430, compound

Participants

Reaction Steps

Dissolve N-[3-(3-chloro-10,11-dihydro-dibenzo[a,d]cyclohepten-5-ylidenemethyl)-phenyl]-methanesulfonamide (200 mg, 0.49 mmol) in EtOAc (30 mL) and add 5% Pt/C (150 mg). Stir for 18 h under an atmosphere of hydrogen. Add 5% Pt/C (200 mg). Stir for 24 h under an atmosphere of hydrogen. Filter and concentrate to give 140 mg crude product. Purify using reverse-phase UV guided HPLC to give 28 mg viscous tan oil, MS (ES) 410 (M−1). HPLC shows 99% purity.

Provenance & Evidence