3-Methylsulfonylaminophenylboronic acid → HCID 68936237, compound

Participants

Reaction Steps

Following the procedures essentially as described in Example 219, below, and using 5-bromomethylene-3-fluoro-10,11-dihydro-5H-dibenzo[a,d]cycloheptene (200 mg, 0.660 mmol) and 3-methanesulfonylaminophenylboronic acid (156 mg, 0.726 mmol), affords 212 mg (82%) of a mixture of geometric isomers of the title compound as a yellow solid. MS (ES) 411 (M+NH4), 392 (M−H); HPLC shows 98% purity.

Provenance & Evidence