HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 59770332, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 5-bromomethylene-10,11-dihydro-5H-dibenzo[a,d]cycloheptene | HCID 5257940 | — |
| Reactant | 4,4,5,5-Tetramethyl-2-[3-(methylsulfanyl)phenyl]-1,3,2-dioxaborolane | HCID 44754769 | — |
| Product | HCID 59770332 | HCID 59770332 | 79% |
Reaction Steps
Following procedures as described in Example 219, mix 5-bromomethylene-10,11-dihydro-5H-dibenzo[a,d]cycloheptene (1 equivalent), 4,4,5,5-tetramethyl-2-(3-methylsulfanyl-phenyl)-[1,3,2]dioxaborolane (1.25 equivalents), 2N Na2CO3 (2 equivalents) and tetrakistriphenylphosphine palladium (0.05 equivalents)in a suitable solvent. Purify the product by silica gel chromatography to obtain a 79% yield of the title compound. MS(ES)=329(+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07411072B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-ccd07765284540a9a5f31ab03c14f059 |
| Source note | uspto-grants-2008_08 |