Toluene → HCID 68933976, compound

Participants

Reaction Conditions

Reaction Steps

Dissolve (2-chloro-10,11-dihydro-dibenzo[a,d]cyclohepten-5-ylidene)acetic acid methyl ester (1 equivalent) in a suitable dry solvent and cool to 0° C. under a dry atmosphere. Add 1M diisobutylaluminum hydride solution in toluene (3 equivalents) dropwise and stir the mixture for one hour. Quench with aqueous citric acid solution and partition between water and ethyl acetate. Dry and evaporate the organic layer to obtain the title compound in 87% yield.

Provenance & Evidence