Sodium Carbonate → HCID 68939746, compound

Participants

Reaction Steps

Following procedures essentially as described in Example 219, mix 5-(1-bromo-2-methoxy-ethylidene)-2-chloro-10,11-dihydro-5H-dibenzo[a,d]cycloheptene (1 equivalent), N-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-methanesulfonamide (1.25 equivalents), 2N Na2CO3 (2 equivalents) and tetrakistriphenylphosphine palladium (0.65 equivalents)in a suitable solvent. Purify the product by silica gel chromatography to obtain a 62% yield of the title compound.

Provenance & Evidence