1-Methoxy-4-methyl-2-(3,3,5,5-tetramethylcyclohex-1-enyl)benzene → 1-Methoxy-4-methyl-2-(3,3,5,5-tetramethylcyclohexyl)benzene

HRID 2218901Notes

Reaction equation

HRID 2218901 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH3:9])=[CH:5][C:4]=1[C:10]1[CH2:15][C:14]([CH3:17])([CH3:16])[CH2:13][C:12]([CH3:19])([CH3:18])[CH:11]=1>CO.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH3:9])=[CH:5][C:4]=1[CH:10]1[CH2:15][C:14]([CH3:17])([CH3:16])[CH2:13][C:12]([CH3:19])([CH3:18])[CH2:11]1

Participants

4

Reactant 1

HCID 231426761-Methoxy-4-methyl-2-(3,3,5,5-tetramethylcyclohex-1-enyl)benzene

Product 1

HCID 231424201-Methoxy-4-methyl-2-(3,3,5,5-tetramethylcyclohexyl)benzeneYield 99.2%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

To a solution of 1-methoxy-4-methyl-2-(3,3,5,5-tetramethylcyclohex-1-enyl)benzene (1.0 g, 3.87 mmol) produced in Example (104a) in methanol (30 mL) was added 10% palladium on carbon (0.6 g, wet), followed by stirring for 12 hours at room temperature and atmospheric pressure under a hydrogen atmosphere. The reaction mixture was filtered through Celite, and the filtrate was concentrated under reduced pressure to give 1.0 g of a crude product of the title compound as a yellow oil.

Workup

  1. filtrationThe reaction mixture was filtered through Celite
  2. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-65a1eb9763704cfc99f2f18dcf4e4a25
Source dataset
uspto-grants-2008_08
Patent number
US07410971B2

Reaction notes

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