HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 4-Bromoethyl-isophthalic acid dimethylester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Reactant | 5-(Methoxycarbonyl)-2-methylbenzoic acid | HCID 22999486 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 4-Bromoethyl-isophthalic acid dimethylester | HCID 53753665 | — |
Reaction Steps
A mixture of (4) (0.96 g, 4.61 mmol), dibenzoylperoxide (56 mg, 0.23 mmol) and N-bromosuccinimide (NBS) (0.82 g, 4.61 mmol) in carbon tetrachloride (20 ml) was heated at reflux for 20 hours. After cooling to room temperature and filteration the solvent was evaporated to give a yellow oil. Flash chromatograph: silica, hexane/EtOAc (7:3) afforded the pure compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07413727B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-6f4713bd9ddb44dd955be17255b13fbc |
| Source note | uspto-grants-2008_08 |