Acetone → 1-Boc-4-isopropylpiperazine

HRID 2218979Notes

Reaction equation

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:14][C:15]([CH3:17])=O>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([CH:15]([CH3:17])[CH3:14])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

Reactant 2

HCID 180Acetone

HCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 105613521-Boc-4-isopropylpiperazine

Procedure

Prepared from acetone and piperazine-1-carboxylic acid tert-butyl ester.

Sources & evidence

ORD record: ord-0a475dfc3b864611a9bbe228fd301e83
Source dataset: uspto-grants-2008_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07414047B2

Reaction notes

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