1H-Azepine → (4-Azepan-1-ylmethyl-phenyl)-{4-(1-ethyl-propyl)-piperazin-1-yl}-methanone

HRID 2218987Notes

Reaction equation

HRID 2218987 reaction equation
[CH2:1]([CH:3]([N:6]1[CH2:11][CH2:10][N:9]([C:12]([C:14]2[CH:21]=[CH:20][C:17]([CH:18]=O)=[CH:16][CH:15]=2)=[O:13])[CH2:8][CH2:7]1)[CH2:4][CH3:5])[CH3:2].[NH:22]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=[CH:23]1>>[N:22]1([CH2:18][C:17]2[CH:20]=[CH:21][C:14]([C:12]([N:9]3[CH2:10][CH2:11][N:6]([CH:3]([CH2:4][CH3:5])[CH2:1][CH3:2])[CH2:7][CH2:8]3)=[O:13])=[CH:15][CH:16]=2)[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 64514761H-AzepineHCID 57478578HCID 57478578, compound

Product 1

HCID 9951331(4-Azepan-1-ylmethyl-phenyl)-{4-(1-ethyl-propyl)-piperazin-1-yl}-methanone

Procedure

Prepared from the product of Example 12 and azepine.

Sources & evidence

ORD record
ord-6ccf0960bde0425a9ba0dc308b696c90
Source dataset
uspto-grants-2008_08
Patent number
US07414047B2

Reaction notes

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