3-(Trifluoromethyl)piperidine → HCID 10047244, compound
Reaction equation
[CH2:1]([N:5]1[CH2:10][CH2:9][N:8]([C:11]([C:13]2[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][CH:14]=2)=[O:12])[CH2:7][CH2:6]1)[CH2:2][CH2:3][CH3:4].[F:21][C:22]([F:30])([F:29])[CH:23]1[CH2:28][CH2:27][CH2:26][NH:25][CH2:24]1>>[CH2:1]([N:5]1[CH2:10][CH2:9][N:8]([C:11]([C:13]2[CH:20]=[CH:19][C:16]([CH2:17][N:25]3[CH2:26][CH2:27][CH2:28][CH:23]([C:22]([F:30])([F:29])[F:21])[CH2:24]3)=[CH:15][CH:14]=2)=[O:12])[CH2:7][CH2:6]1)[CH2:2][CH2:3][CH3:4]Participants
3
Procedure
Prepared from the product of Example 13 and 3-trifluoromethylpiperidine.
Sources & evidence
- ORD record
- ord-baf09357b9ae4894ab5b66940d8215ba
- Source dataset
- uspto-grants-2008_08
- Patent number
- US07414047B2
Reaction notes
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