反应详情

A solution of 1-(benzyloxy)piperidin-2-imine hydrochloride in methanol, containing palladium on charcoal (10%, w/w) was stirred under hydrogen at atmospheric pressure for 3 h. The catalyst was filtered off and the solution was concentrated to dryness under reduced pressure. The residue was triturated with diethyl ether, filtered and dried under high vacuum to afford 2-iminopiperidin-1-ol hydrochloride as a pale yellow solid.

1. filtrationThe catalyst was filtered off
2. concentrationthe solution was concentrated to dryness under reduced pressure
3. customThe residue was triturated with diethyl ether
4. filtrationfiltered
5. customdried under high vacuum