HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18510668, compound → HCID 69195208, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18510668 | HCID 18510668 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 69195208 | HCID 69195208 | 3.8% |
Reaction Steps
) (±)-[4-[[[4,5-dihydro-3-(3-pyridinyl)-5-isoxazolyl]carbonyl]amino]phenyl]phenylmethyl acetate (0.019 mol) was separated into its enantiomers by chiral column chromatography over Chiralcel OJ (eluent: 100% methanol). The desired fraction group was collected and the solvent was evaporated, yielding 0.3 g of (S)-[4-[[[4,5-dihydro-3-(3-pyridinyl)-5-isoxazolyl]carbonyl]amino]phenyl]phenylmethyl acetate (compound 498).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414048B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-bc3c58e2730244cbadd90addee60b92a |
| Source note | uspto-grants-2008_08 |