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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2219166Generated: October 27, 2026

4-(2-(Pyrrolidin-1-yl)ethoxy)aniline → HCID 178419075, compound

https://huagongshe.com/reaction/2219166

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-(Pyrrolidin-1-yl)ethoxy)anilineHCID 6493749—
Reactant3-(hydroxymethylidene)-1H-indol-2-oneHCID 178418741—
ProductHCID 178419075HCID 17841907564%

Reaction Steps

In a manner similar to that described in Example 231, 4-(2-pyrrolidin-1-yl-ethoxy)-phenylamine (767 mg, 1.2 equiv.) and 3-hydroxymethylene-1,3-dihydro-indol-2-one (500 mg, 3.11 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (690 mg, 64%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07414054B2
Source datasetuspto-grants-2008_08
ORD IDord-f487ac12e0544eaba29548d00939c073
Source noteuspto-grants-2008_08