7-Bromoisoquinoline-5-sulfonyl chloride → 7-Bromo-isoquinoline-5-sulfonic acid (2-{[3-(2-benzyl-4-chloro-phenoxy)-propyl]-[bis-(4-methoxy-phenyl)-methyl]-amino}-ethyl)-amide

Participants

Reaction Steps

Using a procedure analogous to Preparation 103, reaction of 7-bromo-isoquinoline -5-sulfonyl chloride with N1-[3-(2-benzyl-4-chloro-phenoxy)-propyl]-N1-[bis-(4-methoxy-phenyl)-methyl]-ethane-1,2-diamine provides the title compound as a foam. ESIMS: m/z 814[(M+H)+, 35Cl, 79Br], 816 [(M+H)+, 37Cl, 79Br or 35Cl, 81Br], 818 [(M+H)+, 37Cl, 81Br].

Provenance & Evidence