HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-Aminoethyl)isoquinoline-5-sulfonamide → HCID 58816130, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-Aminoethyl)isoquinoline-5-sulfonamide | HCID 3544 | — |
| Reactant | Diisobutylaluminum hydride | HCID 14487 | — |
| Reactant | HCID 28831607 | HCID 28831607 | — |
| Product | HCID 58816130 | HCID 58816130 | — |
Reaction Steps
By following a similar procedure as described in Example 1, DIBAL-H reduction of (2-bromo-4-methyl-phenoxy)-acetic acid methyl ester, and subsequent reductive amination with isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide gives the free amine of the title compound as a clear gum. ESIMS: m/z 464 [(M+H)+, 79Br], 466 [(M+H)+, 81Br].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414063B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-e21b948a034c41a2b345b5a9849f9da3 |
| Source note | uspto-grants-2008_08 |