Nitric Acid → HCID 178433493, compound

HRID 2219260Notes

Reaction equation

HRID 2219260 reaction equation
[OH:1][C:2]1[CH:7]=[C:6]([OH:8])[N:5]=[C:4]([CH3:9])[N:3]=1.[N+:10]([O-])([OH:12])=[O:11]>>[OH:1][C:2]1[C:7]([N+:10]([O-:12])=[O:11])=[C:6]([OH:8])[N:5]=[C:4]([CH3:9])[N:3]=1

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 178418389HCID 178418389, compound

Product 1

HCID 178433493HCID 178433493, compoundYield 15%

Procedure

4,6-Dihydroxy-2-methylpyrimidine (1.0 g, 7.9 mmol) was added gradualy to ice-cooled fuming nitric acid (3 ml) stirring. The mixture was stirred for 2 hours cooling with ice and for 1 hour at the room temperature, and then the precipitated crystal was filtered and dried to obtain 207 mg (yield 15%) of 4,6-dihydroxy-2-methy-5-nitropyrimidine.

Workup

  1. stirringThe mixture was stirred for 2 hours
  2. filtrationthe precipitated crystal was filtered
  3. customdried

Sources & evidence

ORD record
ord-3814ee7fc4bb46f9a50752c77cbc4660
Source dataset
uspto-grants-2008_08
Patent number
US07414066B2

Reaction notes

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