HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11097971, compound → HCID 10196523, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11097971 | HCID 11097971 | — |
| Reactant | HCID 68883889 | HCID 68883889 | — |
| Product | HCID 10196523 | HCID 10196523 | 42% |
Reaction Steps
The same procedure as step 3 of example 1 was accomplished, except for using the epoxide compound (300 mg, 1.07 mmol) obtained in step 1 of example 2 and N-(4-trifluoromethoxyphenyl)-N-(2-methyl-2H-tetrazol-5-ylmethyl)amine. The crude product was purified by silica gel column chromatography (developing solvent-n-hexane:ethyl acetate=2:1), to give desired compound (248 mg, yield: 42%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07414068B2 |
| Source dataset | uspto-grants-2008_08 |
| ORD ID | ord-e6b097a50120462aae4cf0e9be1aec43 |
| Source note | uspto-grants-2008_08 |