HCID 69215565, compound → HCID 9984224, compound

Participants

Reaction Steps

The same procedure as step 3 of example 1 was accomplished, except for using (2R,3R,4R)-6-bromo-2-methyl-2-dimethoxymethyl-3,4-epoxy-3,4-dihydro-2H-1-benzopyran (198 mg, 0.63 mmol) and N-(4-fluorophenyl)-N-(2-methyl-2H-tetrazol-5-ylmethyl)amine (130 mg, 0.63 mmol). The crude product was purified by silica gel column chromatography (developing solvent-n-hexane:ethyl acetate=4:1), to give desired compound (175 mg, yield: 53%).

Provenance & Evidence