Carbon Tetrachloride → HCID 68508363, compound

Participants

Reaction Steps

To a solution of (1S,3′R,4′S,5′S,6′R)-3′,4′,5′-tris-benzyloxy-6′-benzyloxymethyl-3,3′,4,4′,5′,6′-hexahydro-8-hydroxymethyl-spiro[2-oxa-9-thia-fluorene-1,2′-[2H]pyran] (72 mg, 0.10 mmol) in dichloromethane (1 mL) were added carbon tetrachloride (48 μL, 0.5 mmol) and triphenylphosphine (131 mg, 0.5 mmol). The resultant solution was then stirred for 3 hours at room temperature. The reaction solution was concentrated under reduced pressure, and the resulting residue was purified by silica gel column chromatography (developing solution=ethyl acetate:n-hexane (1:2)), to thereby obtain the titled compound (42 mg, 48%).

Provenance & Evidence