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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2219348Generated: October 30, 2026

Benzene, 1-fluoro-4-(trifluoromethyl)- → HCID 23725752, compound

https://huagongshe.com/reaction/2219348

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-fluoro-4-(trifluoromethyl)-HCID 67873—
ReactantHCID 178432460HCID 178432460—
ProductHCID 23725752HCID 237257529%

Reaction Steps

As described for Example 57, 5-methyl-4-(2-methyl-1H-imidazol-4-yl)-3-phenyl-isoxazole (70 mg, 0.3 mmol) using 4-fluorobenzotrifluoride instead of 4-fluoroacetophenone was converted to the title compound (10 mg, 9%) which was obtained as a light yellow solid. MS: m/e=384.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07414061B2
Source datasetuspto-grants-2008_08
ORD IDord-5ada05fc4fd049b596c4ad556beebc8a
Source noteuspto-grants-2008_08